Pathophysiology of Disseminated Intravascular Coagulation(DIC)
Number of View :152Under homeostatic conditions, the body is maintained in a finely tuned balance of coagulation and fibrinolysis. The activation of the coagulation cascade yields thrombin that converts fibrinogen to fibrin; the stable fibrin clot being the final product of hemostasis. The fibrinolytic system then functions to break down fibrinogen and fibrin. Activation of [...]
Disseminated Intravascular Coagulation,DIC(epidemiology,pathophysiology,causes,signs&symptoms,diagnosis,treatment and prognosis)
Number of View :198Disseminated intravascular coagulation (DIC), also known as consumptive coagulopathy, is a pathological activation of coagulation (blood clotting) mechanisms that happens in response to a variety of diseases. DIC leads to the formation of small blood clots inside the blood vessels throughout the body. As the small clots consume coagulation proteins and platelets, [...]
ISCHAEMIC HEART DISEASE (IHD)
Number of View :174This represents a group of disease of the heart resulting from ischemia. The underlying cause is narrowing of the coronary arteries usually from atherosclerosis an a few other causes. EPIDEMIOLOGY IHD is the leading cause of death in most developed countries. The prevalence is used to express the prevalence of atherosclerosis since [...]
Hypoxic Drive in COPD patient: Clinical application
Number of View :52165 years old malay man presented to casualty because of progressive worsening of shortness of breath. He was treated as acute exarcebation of COPD secondary to URTI and was given oxygen 3L/ min via nasal prong. His SPO2 concentration on nasal prong was 65%. Will you increase the oxygen dosage? Notes: Our [...]