Metabolic Acidosis
Number of View :151 Definition Acid-Base physiology Anion gap Differential diagnosis of metabolic acidosis with high anion gap Lactic acidosis Oxidative phosphorylation Types of Lactic acidosis Treatment of Lactic Acidosis Metabolic Acidosis (primary fall in serum bicarbonate) A condition that causes a primary fall in serum [...]
The Unconcious Patients (Patients in Coma) and Causes of Coma
Number of View :71The Unconscious Patients (Patients in Coma) When we talk about the unconscious patients, we talk about patients in coma. Coma is one of the most common medical emergencies in hospitals. The cause of coma in many patients may not be instantly obvious in some patients. However, if a doctor is able to give attention [...]
Treatment of Disseminated Intravascular Coagulation,DIC
Number of View :76The only effective and reliable treatment is the reversal of the underlying cause. Anticoagulants are given exceedingly rarely when thrombus formation is likely to lead to imminent death (such as in coronary artery thrombosis or cerebrovascular thrombosis). Platelets may be transfused if counts are less than 5,000-10,000/mm3 and massive hemorrhage is occurring, [...]
Diagnosis of Disseminated Intravascular Coagulation,DIC
Number of View :96* Severe cases with hemorrhage: The PT and APTT are usually very prolonged and the fibrinogen level markedly reduced. High levels of fibrin degradation products, including D-dimer, are found owing to the intense fibrinolytic activity stimulated by the presence of fibrin in the circulation. There is severe thrombocytopenia. The blood film may [...]
Causes of Disseminated Intravascular Coagulation(DIC)
Number of View :75DIC can occur in the following conditions: * Cancers of lung, pancreas, prostate and stomach, as well as acute myeloid leukemia (particularly APML) * Obstetric: abruptio placentae, pre-eclampsia, amniotic fluid embolism * Massive tissue injury: Trauma, burns, extensive surgery * Infections: Gram-negative sepsis, Neisseria meningitidis, Streptococcus pneumoniae, malaria, histoplasmosis, aspergillosis, Rocky mountain [...]